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Jun-Rong Du
Head of Department of Pharmacology&Biopharmaceutics
Key Laboratory of Drug-Targeting and Drug Delivery System of Education Ministry
West China School of Pharmacy
Sichuan University, Chengdu 610041, China
Tel/Fax: (+86) 28 85503938
E-mail:dujr07@gmail..com
 
Education
2002-2005:  D. Sc. at Department of Applied Biology&Chemical Technology, The Hong Kong Polytechnic University
1986-1989:   M. Sc. at Department of Pharmacology, West China University of Medical Sciences
1981-1986:   B. Sc. at School of Pharmacy, West China University of Medical Sciences
                                          
Academic Career
1990-  Staff as Assistant Professor, Associate Professor, or Professor of Pharmacology at West China School of Pharmacy, Sichuan University
 
Professional/Consulting Activities:
Elected member, Chinese Pharmacology Association: Cardiovascular Pharmacology Committee; Cancer Pharmacology Committee.
 
Administrative Duties:
Head of Department of Pharmacology&Biopharmacology, West China School of Pharmacy, Sichuan University .
 
 
Research Areas
Preclinical Pharmacodynamics of new drugs aimed at the treatment of cancer, cardiovascular and neurovascular diseases; Potential therapeutic targets for cerebral ischemia; Screening of natural active compounds.      
Selected Publications
(1)Kuang X, DU J*, LIU Y, ZHANG G, et al. Postischemic Administration of Ligustilide Ameliorates Cognitive Dysfunction and Brain Damage induced by Permanent Forebrain Ischemia in Rats. Pharmacol Biochem Behav  2008,88(3):213-221.
(2)Yu Y, Du J*,Wang C, Qian Z. Protection against hydrogen peroxide-induced injury by Z-ligustilide in PC12 cells. Exp Brain Res 2008;184(3):307-314.
(3)Peng H, Du J*,Zhang G, Kuang X, Liu  Y, Qian ZM, Wang C. Neuroprotective effects of Z-ligustilide against permanent focal ischemic damage in rats. Biol Pharm Bull 2007;30:309-312.
(4)Du J, Yu Y, Yao Y, Bai B, Zong X, Wang C, Qian Z. Ligustilide reduces phenylephrine induced-aortic tension in vitro but has no effect on systolic pressure in spontaneously hypertensive rats. Am J Chin Med 2007;35: 487-496
(5)Chang Y, Qian Z, Du J, Zhu L, Xiu Y,Li L, Wang C, Wang Q, Ge X, Ho K, Niu L, Ke Y .Ceruloplasmin expression and its role in iron transport in C6 cells. Neurochem Int 2007;50(5):726-733.
(6) Du J,Yu Y, Ke Y, Wang C, Zhu L, Qian Z. Ligustilide  attenuates pain behavior induced by acetic acid or formalin. J  Ethnopharmacol  2007;112(1):211-214.
(7) Qian Z, Chang Y, Leung G, Du J, Zhu L, Wang Q, Niu L, Xu Y, Yang L, Ho K, Ke Y. Expression of ferroportin1, hephaestin and ceruloplasmin in rat heart. Biochim Biophys Acta 2007;1772:527-532.
(8)Kuang X, Yao Y, Du  J*, Liu  YX, Wang C, Qian Z. Neuroprotective  role of Z-ligustilide against forebrain ischemic injury in ICR mice. Brain Res  2006;1102:145-153.
(9)Du J,Bai B, Kuang X, Yu Y, Wang C, Xiu Y, Tzang A, Qian Z. Ligustilide inhibits spontaneous and agonists- or K+depolarization-induced contraction of rat uterus. J  Ethnopharmacol 2006;108:54-58.
(10)Chang Y, Ke Y, Du J, Ho K, Zhu L, Gu XS, Xu Y, Wang Q, Li L, Wang C, Halpern GM, Qian ZM. Increased DMT1 expression might be associated with the neurotoxicity of L-DOPA. Molecular Pharmacol 2006;69(3):968-974.
(11)Ke Y, Ho K, Du J, Zhu L, Xu Y, Wang Q, Wang CY, Li L, Ge X, Chang Y, Qian ZM.Role of soluble ceruloplasmin in iron uptake by midbrain and hippocampus neurons.J Cell Biochem 2006;98(4):912-919.
(12)Chen Y, Qian Z, Du J, Duan X, Chang Y, Wang Q, Wang C, Ma Y, Xu Y, Li L, Ke Y. Iron loading inhibits ferroportin1 expression in PC12 cells. Neurochem Int 2005;47(7):507-513.
(13)Ke Y, Chang Y, Duan X, Du J, Zhu L, Wang K, Yang X, Ho K, Qian Z.Age-dependent and iron-independent expression of two mRNA isoforms of divalent metal transporter 1 in rat brain. Neurobiol Aging 2005;26(5):739-748.
(14)Du J *, Li X, Zhang R, Qian Z. Tanshinone inhibits intimal hyperplasia in the ligated carotid artery in mice. J Ethnopharmacol 2005;98(3):319-322.
   
MAIL to Prescent
Main campus address:
Wangjiang campus: section of Chengdu No. 24 Southern Yihuan Code: 610065 | 29 Jiuyanqiao WangjiangRoad, Chengdu Zip: 610064
Huaxi Campus: Chengdu, People’s SouthRoad was on the 17th Zip: 610041
Jiang’an Campus: Shuangliu County, Chengdu, Sichuan road Zip: 610207
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