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YAN CHENG
YAN CHENG
Associate professor, Ph.D
West China School of pharmacy, Sichuan University
No.17, Block 3, South Renmin Road, Chengdu, Sichuan, 610041, P.R.China
yancheng@scu.edu.cn
 
Academic Appointments:
Associate professor, West China School of Pharmacy, Sichuan University
Visiting associate professor, School of Medicine, Stanford University
Adjunct professor, School of Pharmacy and Health Sciences, University of the Pacific
 
Professional Education:  
Kyoto University, Kyoto, Japan. Ph.D in Pharmaceutical sciences, 2012
Sichuan University, Chengdu, China. MA in Pharmaceutical sciences, 2007
Sichuan University, Chengdu, China. BA in Pharmaceutical sciences, 2004
 
Research Areas:
1.       Development of imaging assays to monitor molecular events in living subjects including patients, such as positron emission tomography (PET), optical (fluorescence, bioluminescence), and photoacoustic imaging.
2.       Development of targeted imaging probes for multiple modalities, including small molecules, engineered proteins, and nanoparticles.
 
Funding:
1.       National Natural Science Foundation of China (No. 81402891)
2.       Scientific Research Foundation for Outstanding Youth Scholars from Sichuan University (No. 2015SCU04A37)
3.       Scientific Research Foundation for Youth Scholars from Sichuan University (No. 2012SCU11091)
 
Publications:
1)  Yan Cheng, Biyue Zhu, Yue Deng, Zhirong Zhang. In vivo detection of cerebral amyloid fibrils with smart dicynomethylene-4H-pyran-based fluorescence probe. Anal. Chem. 2015, 87, 4781-4787.
2)  Yan Cheng, Biyue Zhu, Xue Li, Zhirong Zhang. A Pyrane Based Fluorescence Probe for Noninvasive Pprediction of Cerebral β-Amyloid Fibrils. Bioorg. Med. Chem. Lett. 2015, 25, 4472-4476.
3) Masahiro Ono *,a Yan Cheng,a Hiroyuki Kimura, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Shimpei Iikuni, Yoko Okamoto , Masafumi Ihara, Ryosuke Takahashi, Hideo Saji. Development of Novel (123)I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer's Disease. PLoS One2013, 8, e74104. (a contributes equally)
4) Yan Cheng, Masahiro Ono*, Hiroyuki Kimura, Hideo Saji. Technetium-99m Labeled Pyridyl Benzofuran Derivatives as Single Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Alzheimer’s Brains. J. Med. Chem. 2012, 55, 2279-2286.
5)Masahiro Ono*, Yan Cheng, Hiroyuki Kimura, Mengchao Cui, Shinya Kagawa, Ryuichi Nishii, Hideo Saji. Novel 18F-Labeled Benzofuran Derivatives with Improved Properties for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques in Alzheimer's Brains. J. Med. Chem. 2011, 54, 2971-2979.
6)Yan Cheng, Masahiro Ono*, Hiroyuki Kimura, Shinya Kagawa, Ryuichi Nishii, Hideo Saji. Fluorinated Benzofuran Derivatives for PET Imaging of β-Amyloid Plaques in Alzheimer's Disease Brains. ACS Med. Chem. Lett. 2010, 1, 321-325.
7)Yan Cheng, Masahiro Ono*, Hiroyuki Kimura, Shinya Kagawa, Ryuichi Nishii, Hideo Saji. A Novel 18F-Labeled Pyridyl Benzofuran Derivative for Imaging of β-Amyloid Plaques in Alzheimer's Brains. Bioorg. Med. Chem. Lett. 2010, 20, 6141–6144.
8) Yan Cheng, Fluorinated Benzofuran Derivatives for PET Imaging of β-Amyloid Plaques in Alzheimer’s Disease Brains. World Molecular Imaging Congress, Kyoto, Japan. 2010
9) Yan Cheng, Smart DCM-Based Fluorescence Probes for Cerebral β-Amyloid Plaques. World Molecular Imaging Congress, Honolulu, USA. 2015
10) Yan Cheng, A Smart Styrylpyrazine Based Fluorescence Probe for Selective Visualization of Fibrillar  Tau Pathology, World Molecular Imaging Congress, Philidephia, USA. 2017
MAIL to Prescent
Main campus address:
Wangjiang campus: section of Chengdu No. 24 Southern Yihuan Code: 610065 | 29 Jiuyanqiao WangjiangRoad, Chengdu Zip: 610064
Huaxi Campus: Chengdu, People’s SouthRoad was on the 17th Zip: 610041
Jiang’an Campus: Shuangliu County, Chengdu, Sichuan road Zip: 610207
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